Yoo Hye Jung, a rebellious teenager, ends up in the care of her grandmother. She doesn't back down from anyone, whether adults, another youth, or even gang members. Unfortunately, she butts heads with Professor Hong Ji-Hong who turns out to be her new classroom teacher.
Jo-Hong takes a new approach in instructing Hye Jung. When Ji-hong and Hye-Jung save a pregnant woman, she becomes inspired and decides to change her life around. Hye-Jung finds friendship in Chun Soon-hee and Jin Seo-woo.
Seo-Woo's jealousy leads to drastic events and destroys the friendship bonds. Soon-Hee stays loyal to Hye-Jung. Kang Mal-Soon, Hye-Jung's grandmother, goes in for an operation. Ji Hong tenders his resignation as a teacher.
13 years after the big rift, Hye-Jung transfers to Gul Il Medical Center as a Surgeon. Although happy to reunite with her friend, Soon-Hee, she is not welcomed by everyone. She starts off on the bad side of Dr. Jung Yoon-Do and some old enemies.
Ji-Hong and Hye-Jung have a sparring match and later confesses his feelings to her. Director Myung-Ho plots to maintain and solidify his control over the hospital. Hye-Jung discovers a suspicious person.
Hye-Jung asks Ji Hong to retrieve a patient's file that she does not have access to. Hye-Jung is surprised by a new patient. Ji-Hong steps up his courtship game.
As budding romances start budding and dying, things start popping at Soon-Hee's "Sooni Hawaii" cafe. Ji-Hong takes on a special patient. Hye-Jung is surprised by an old friend which leaves Yoon-Do and Ji-Hong feeling jealous.
Soo-Chul is badly injured in a motorcycle accident. Doo-Shik attempts to clear his reputation. Lee-Soo-Jung, an Olympic Gold Medalist, undergoes surgery. Yoo Min-Ho attempts to reestablish family ties with Hye-Jung. A celebration party at Sooni Hawaii takes a drastic turn.
A quality fishing trip gets broken up when news of a unannounced National Tax Service inspection on the hospital is received. Hye-Jung grants Intern Kang-Soo and Nurse Hyun Soo-Jin a special favor.
Old scars for Ji-Hong to do some self-reflection after he oversteps his boundaries with Hye-Jung. Do Jo In-Joo returns to Guk Il Medical Center as Staff Surgeon in the general surgery department. A distraught husband brings a wife in that has fallen and is comatose. Jeon Gook-Hwan threatens Hong Doo-Shik.
Jin Sung-Jong takes the helm as Director. Patient Jo Su-Ji's case takes an unexpected turn. Empty nested Yoon-Do's home isn't so sweet since encroachers arrived.
Director Jin Myung-Hoon is basking in his own glory. Nam Ba-Ram brings his children in for a checkup. Office romance is in full bloom and hard for Ji-Hong and Hye-Jung to hide. Yoon-Do is missing his own sweet pad.
Ji-Hong wants to start the process of healing by identifying old scars. Nam Ba-Ram is at wits end from coping with the pressures concerning payment demands. Second Year Resident Doctor Ahn Jong-Dae is on the lamb due to the abuse he has suffered.
Hye-Jung and Mr. Nam help each other to heal some of their life's trauma. Jong-Dae is busted and dragged back to work. Seo-Woo does some major growing up. A couple on their wedding day are involved in an automobile accident. The beagles have taken over Yoon-Do's home, so he goes slumming.
Kang-Soo runs into trouble and starts doubting himself. Soon-Hee tells Hye-Jung she is going to divorce her. Complications arise in Congressmen Nam In-Soon's case. Jin Myung-Hoon seizes an opportunity to rid himself of a pest.
Hye-Jung goes before the Disciplinary Board. Kang-Soo collapses. Hye Jung finally gets the anesthesiology report, but things don't go according to plan.
Hye-Jung threatens Myung-Hoon. Ji-Hong is transferred to a research branch. The Board convenes to vote on the Geriatrics Center issue. Ji-Hong and Tae-Ho try to find out what Doo-Shik had on Sung-Jong and Myung-Hoon.
Things are turning disastrous for the Jin family. Seo-Woo discovers the secret between Hye-Jung and her father. Stress is taking a toll on her father, Myung-Hoon.
