Adriana left Oscar. Now he lives with Gaby and Mica. Valentin came out of the closet and tried to be happy in this new stage of his life. Barbara and Leo adopt Carmen in a 3-way open relationship.
Adriana blames Siena for everything that has happened since they met. She's introduced to Astrid, Siena's Guru; and both convince Adriana to live free. Barbara's mom arrives home unannounced.
Adriana joins Astrid and Siena to a Game of Keys. Barbara is annoyed with her mother. Gaby notices that Oscar doesn't care what happens to their relationship.
Leo is convinced that his true vocation is to be a Stripper. Valentin tries to confess to his father his sexuality. Astrid organizes a Game of Keys in her house for Siena to forget about Adriana.
In this new Game of Keys, the experiences will be varied. Some will find love, others only dissapointment. They're keys will make them play with the person they hate the most.
Adriana and Barbara overcome their first Bachelorette Party planned by them both. Amelia organized a baby shower for Gaby's baby. The ingredients are set for an explosive party.
Adriana tries the imposible to recover Mica, while she continues her romance with Guillermo and breaks Siena's heart. Astrid leaves the country. The future appears hopeless for Gaby and Oscar.
They all travel to the beach to celebrate Leonardo and Barbara's wedding. The wedding is not a game, but everything that'll happen there will leave questions for a long time.
